Using medical AI as ‘autopilot’ risks deskilling of clinicians, caution doctors and aviation safety experts
- INSIGHT communications team
- 6 hours ago
- 5 min read
As artificial intelligence (AI) becomes increasingly integrated into healthcare services, there are important lessons that the medical profession can learn from the aviation industry, which faced widespread loss of human skills after the adoption of autopilot.
While calls for medicine to learn from aviation are not new, a group of clinicians and flight safety experts have collaborated to move this conversation beyond familiar analogies by looking at where the comparison is meaningful and where it fails, in order to examine how automation has reshaped pilot expertise - and what this might mean for clinicians working alongside AI.
Clinical researchers from University College London Institute of Ophthalmology and Moorfields Eye Hospital NHS Foundation Trust worked with the flight safety department of Lufthansa on recommendations for future-proofing the clinical workforce and improving patient outcomes. Published in npj Digital Medicine, the perspective piece argues that healthcare must shift from viewing AI as an "autopilot" to embracing it as a "digital copilot".
The Automation Paradox
The authors highlight the "automation paradox" in which increasing automation erodes human skills and awareness. In aviation, this led to the term "children of the magenta line", a generation of younger pilots who became so dependent on the magenta autopilot navigation line on screen they lacked the skills to fly manually.

Lead author Ariel Ong said: "Medicine risks repeating aviation's early automation mistake of placing too much faith in the machine while losing critical skills. Aviation learned that the goal was never to replace the pilot, but to enable rigorous simulation training. We argue for the need to embrace that same philosophy to ensure clinician judgement is not eroded as AI becomes increasingly embedded in healthcare."

Senior author Josef Huemer commented: “Medicine has already borrowed heavily from the aviation industry. For example, surgical checklists, safety time-outs, human factors simulation training, and a culture of incident reporting and analysis that allows healthcare workers to feel safe reporting errors without retribution, all have their origins in flight safety. With AI now poised to reshape medical workflows, we should consider how we can learn lessons on automation from the aviation industry to avoid making the same mistakes.”
Key Recommendations
Informed by lessons from flight safety, the authors make five recommendations.
Benchmark clinicians and monitor unaided performance.
Institutions should assess real-world clinician performance without AI assistance and set minimum unaided practice requirements after AI deployment, just as pilots have to maintain manual flying skills during routine flights with ongoing monitoring to detect overreliance.
Prioritise independent reasoning in early training.
For younger clinicians trained in AI-rich environments, the risk shifts from deskilling to "never skilling" or "mis-skilling." Evidence suggests learners develop shallower knowledge with AI tools than through self-directed learning. Early training should build independent reasoning before automation is introduced, allowing AI to scaffold rather than substitute skill development.
Ensure clinicians understand AI limitations.
Medical schools should teach AI literacy and technical competence in using AI tools. These skills should then be maintained and enhanced through professional development so clinicians are equipped to identify AI bias and other shortcomings.
Introduce scenario-based simulation training.
Mandatory simulator training that recreates AI failure scenarios should be adopted, similar to aviation practice. This should extend beyond traditional surgical simulation to include development of dedicated simulation environments for non-surgical, end-to-end clinical workflows where AI is or might be used. In addition, routine AI settings, unannounced "surprise breaks" from AI can assess a clinician’s readiness to operate safely without automation.
Cultivate operational understanding
Clinicians should have a fundamental grasp of how an AI tool arrives at a decision and know when to override it. This mirrors aviation's "golden rule": understand the automated system at all times. When that understanding is lost, reduce automation step by step until situational awareness is restored.
The authors conclude that regulation should evolve beyond certifying AI as a medical device to address competence, accountability, and safety within the human-AI partnership. Humans and AI should ideally function as “co-intelligent” partners, combining human contextual reasoning with algorithmic speed and pattern recognition. Patients, too, favour this approach, consistently responding in surveys that they prefer clinicians to lead in decision-making, with AI assisting.

Read the recommendations in full: Flight rules for clinical AI: lessons from aviation for human-AI collaboration in medicine | npj Digital Medicine
Lead author Ariel Ong is an ophthalmology registrar at Oxford University Hospitals NHS Foundation Trust, a doctoral fellow at University College London, Honorary Clinical Research Fellow at Moorfields Eye Hospital NHS Foundation Trust, and Data Lead for the INSIGHT Eye and Oculomics Health Data Research Hub. Ariel’s doctoral fellowship is jointly funded by the National Institute for Health and Care Research and Moorfields Eye Charity.
Senior author Josef Huemer is a consultant ophthalmologist at Moorfields Eye Hospital NHS Foundation Trust
About the INSIGHT Eye and Oculomics Health Data Research Hub
INSIGHT is the world's largest ophthalmic imaging bioresource, with over 30 million eye images linked to clinical data. An NHS initiative founded in 2019 and led by Moorfields Eye Hospital, INSIGHT makes routinely collected patient eye data available for approved research that could lead to improvements in diagnosis, care and treatment of eye diseases, as well as systemic disease such as stroke and Alzheimer’s. INSIGHT’s mission is to improve healthcare for the benefit of patients, the NHS and wider society by enabling safe and trusted research access to anonymised data for research and innovation. For more information, please visit https://www.insight.hdrhub.org/
About Moorfields Eye Hospital NHS Foundation Trust
Moorfields Eye Hospital NHS Foundation Trust is one of the leading providers of eye health services in the UK and a world class centre of excellence for ophthalmic research and education. Our main focus is the treatment and care of NHS patients with a wide range of eye problems, from common complaints to rare conditions that require treatment not available elsewhere in the UK. Our unique patient case mix and the number of people we treat mean that our clinicians have expertise in discrete ophthalmic sub-specialties.
We treat people in 20 locations in and around London, the south east and Bedford, enabling us to provide expert treatment closer to patients’ homes. We also operate commercial divisions that provide care to private patients in both London and the Middle East.
With our academic partners at the UCL Institute of Ophthalmology, Moorfields is recognised as a leading centre of excellence in eye and vision research. Together we form one of the largest ophthalmic research sites in the world, with the largest patient population in Europe or the USA. We publish more scientific papers than any other eye and vision research site and have an extensive joint research portfolio.
About UCL Institute of Ophthalmology
The UCL Institute of Ophthalmology is one of a number of specialised research centres within UCL (University College London) and is, together with Moorfields Eye Hospital, one of the leading centres for eye research worldwide. The combination of the institute’s research with the resources of Moorfields Eye Hospital opens the way for advances at the forefront of vision research. Close collaboration with other academic partners and with industry extends its impact. The institute has been named as the best place to study ophthalmology in the 2017 Centre for World University Rankings (CWUR). For more information, please visit www.ucl.ac.uk
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