Data Use Application 014
Lead applicant organisation name
Name of the legal entity that signs the contract to access the data.
Moorfields Eye Hospital NHS Foundation Trust. Lead applicant: Caitlín Campbell, Research student PhD
Project title
The title of the project/research study request that the applicant is investigating through the use of health data.
Examining the Nature of Glaucomatous Visual Field Loss in Myopia Within 'Real-World' Clinics
Lay summary
A concise and clear description of the project. This should outline the problem, objective and the expected outcomes in language that is understandable to the general public.
Glaucoma is the leading cause of irreversible blindness, characterised by progressive degeneration of nerve cells and the associated loss of side vision (visual field). Early detection and treatment are crucial to avoid permanent vision loss. However, the detection of glaucoma is a significant clinical challenge, this being most difficult in myopic (short-sighted) patients.
Myopia is a common refractive error where the eye length is too great for its optical power, with changes in the structure and function of the myopic eye bearing a close resemblance to those that occur in glaucoma. Currently, no clinical test has been designed to specifically differentiate changes in the eye that occur in myopia from those that occur in glaucoma. Consequently, myopic patients undergo long periods of monitoring to detect worsening of their eye structure or vision over time (progression) that is characteristic of glaucoma, likely leading to delayed diagnosis and treatment.
In this project we aim to examine which visual field regions are most useful to detect and predict glaucomatous vision changes in myopic patients. Secondly, we will then quantify NHS costs associated with the management of myopic and non-myopic patients within glaucoma services.
Public benefit statement
A description in plain English of the anticipated outcomes, or impact of project on the general public.
This will be the first study to determine if quicker and more effective access to diagnosis and treatment for myopic glaucoma patients would be possible by targeting special regions of the visual field. It will thus highlight potential areas for improvement in service delivery, aid resource planning, and highlight potential economic benefits relating to improved glaucoma detection strategies in myopic eyes.
Latest approval date
The last date the data access request for this project was approved by a data custodian.
6 May 2025
Dataset(s) name
The name of the dataset(s) being accessed.
Bespoke glaucoma dataset
Access type
Determines whether the data will be accessed with an Trusted Research Environment (TRE) or via data release.
Data provisioned to the research applicant through INSIGHT's Secure Research Environment.
Data sensitivity level
The level of identifiability of the data being accessed, as defined by Understanding Patient Data.
Anonymised